17 columbushosp.org ‘Nothing short of lifesaving’ Clark asked Kolli about esketamine (brand name Spravato), a newer type of medicine for people with treatment-resistant depression, or for those diagnosed with major depressive disorder with suicidal thoughts. Kolli determined that Clark would be a candidate for the medicine, which targets a neurochemical called glutamate. “Blocking certain glutamate receptors improves depressive symptoms,” Kolli said. Up to 70% of people with treatment-resistant depression benefit from taking esketamine, Kolli noted. Clark visits the infusion center at Columbus to receive treatments, which are given as a nasal spray. Afterward, a nurse monitors her vital signs for a couple hours to ensure there are no side effects. Clark is grateful for everyone at Columbus who played a part in making esketamine treatments available locally for those who, like her, continue to struggle with depression after trying two or more antidepressant medications. “These treatments have been nothing short of lifesaving for me, and I am immensely thankful for the support and care I have received throughout my journey,” she said. While Clark still lives with depression, her symptoms have improved. She praised Kolli for creating an individualized treatment plan and researching options on her behalf. “He wants me to feel better, and he is genuine about that,” Clark said. “The most reassuring thing to me about the care I received was those who were in charge of my care,” she added. “Not only did Dr. Kolli oversee things, but he has a wonderful nurse in charge of all Spravato treatments. Finally, the nurses who administer the Spravato are kind, compassionate and excellent at what they do. They create a nonjudgmental environment.” ‘It’s OK to seek help’ By sharing her story about her years-long struggles with depression, Clark hopes that it might inspire other people to seek the help they need and deserve. Her message for anyone who may need to hear it: “Don’t give up,” Clark said. “It’s not easy to ask for help, but it’s worth it. Just being willing to tell someone you’re not OK is actually OK. It is OK to seek help.” If you need help right now If you want to talk, you can call or text the 988 Suicide and Crisis Lifeline at 988. In a life-threatening emergency, call 911. Connect to Columbus Psychiatry Clinic Visit columbuspsychiatry.org or call 402-562-4765 to learn more about the clinic.
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